Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection

Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection

Middle East respiratory syndrome coronavirus (MERS-CoV) is the second novel zoonotic coronavirus to emerge in the 21st century and cause outbreaks of severe respiratory disease. More than 2,200 cases and 800 deaths have been reported to date, yet there are no licensed vaccines or treatments. Coronav...

Full description

Bibliographic Details
Main Authors: Courtney E. Comar, Stephen A. Goldstein, Yize Li, Boyd Yount, Ralph S. Baric, Susan R. Weiss
Format: Article
Language:English
Published: American Society for Microbiology 2019-03-01
Series:mBio
Subjects:
MERS-CoV
coronavirus
interferon antagonist
viral accessory proteins
Online Access:https://doi.org/10.1128/mBio.00319-19

Internet

https://doi.org/10.1128/mBio.00319-19

Similar Items