High Endothelial Venules: A Vascular Perspective on Tertiary Lymphoid Structures in Cancer

High Endothelial Venules: A Vascular Perspective on Tertiary Lymphoid Structures in Cancer

High endothelial venules (HEVs) are specialized postcapillary venules composed of cuboidal blood endothelial cells that express high levels of sulfated sialomucins to bind L-Selectin/CD62L on lymphocytes, thereby facilitating their transmigration from the blood into the lymph nodes (LN) and other se...

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Bibliographic Details
Main Authors: Gerlanda Vella, Sophie Guelfi, Gabriele Bergers
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
high endothelial venules
tertiary lymphoid structures
tumor endothelial cells
tumor immunity
immunotherapy
lymphotoxin beta receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.736670/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.736670/full

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