Puromycin aminonucleoside triggers apoptosis in podocytes by inducing endoplasmic reticulum stress
Background: Puromycin aminonucleoside (PAN) is a known podocytotoxin. PAN-induced nephrosis is a widely used animal model for studying human idiopathic nephrotic syndrome. Abnormal protein accumulation associated with podocyte-specific endoplasmic reticulum (ER) stress damages cells structurally and...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Korean Society of Nephrology
2018-09-01
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Series: | Kidney Research and Clinical Practice |
Subjects: | |
Online Access: | https://doi.org/10.23876/j.krcp.2018.37.3.210 |