Puromycin aminonucleoside triggers apoptosis in podocytes by inducing endoplasmic reticulum stress

Background: Puromycin aminonucleoside (PAN) is a known podocytotoxin. PAN-induced nephrosis is a widely used animal model for studying human idiopathic nephrotic syndrome. Abnormal protein accumulation associated with podocyte-specific endoplasmic reticulum (ER) stress damages cells structurally and...

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Bibliographic Details
Main Authors: Seo-Yoon Min, Dong-Soo Ha, Tae-Sun Ha
Format: Article
Language:English
Published: The Korean Society of Nephrology 2018-09-01
Series:Kidney Research and Clinical Practice
Subjects:
Online Access:https://doi.org/10.23876/j.krcp.2018.37.3.210