The gastric CB1 receptor modulates ghrelin production through the mTOR pathway to regulate food intake.

Over the years, the knowledge regarding the relevance of the cannabinoid system to the regulation of metabolism has grown steadily. A central interaction between the cannabinoid system and ghrelin has been suggested to regulate food intake. Although the stomach is the main source of ghrelin and CB1...

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Bibliographic Details
Main Authors: Lucia L Senin, Omar Al-Massadi, Cintia Folgueira, Cecilia Castelao, Maria Pardo, Silvia Barja-Fernandez, Arturo Roca-Rivada, Maria Amil, Ana B Crujeiras, Tomas Garcia-Caballero, Enrico Gabellieri, Rosaura Leis, Carlos Dieguez, Uberto Pagotto, Felipe F Casanueva, Luisa M Seoane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3841176?pdf=render