The translational regulators GCN-1 and ABCF-3 act together to promote apoptosis in C. elegans.

The proper regulation of apoptosis requires precise spatial and temporal control of gene expression. While the transcriptional and translational activation of pro-apoptotic genes is known to be crucial to triggering apoptosis, how different mechanisms cooperate to drive apoptosis is largely unexplor...

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Bibliographic Details
Main Authors: Takashi Hirose, H Robert Horvitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4125083?pdf=render