Barium chloride injures myofibers through calcium-induced proteolysis with fragmentation of motor nerves and microvessels

Barium chloride injures myofibers through calcium-induced proteolysis with fragmentation of motor nerves and microvessels

Abstract Background Local injection of BaCl2 is an established model of acute injury to study the regeneration of skeletal muscle. However, the mechanism by which BaCl2 causes muscle injury is unresolved. Because Ba2+ inhibits K+ channels, we hypothesized that BaCl2 induces myofiber depolarization l...

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Bibliographic Details
Main Authors: Aaron B. Morton, Charles E. Norton, Nicole L. Jacobsen, Charmain A. Fernando, D. D. W. Cornelison, Steven S. Segal
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Skeletal Muscle
Subjects:
Skeletal muscle
Motor innervation
Capillary supply
Neuromuscular junction
Online Access:http://link.springer.com/article/10.1186/s13395-019-0213-2

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http://link.springer.com/article/10.1186/s13395-019-0213-2

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