Mouse Cytomegalovirus Differentially Exploits Cell Surface Glycosaminoglycans in a Cell Type-Dependent and MCK-2-Independent Manner

Mouse Cytomegalovirus Differentially Exploits Cell Surface Glycosaminoglycans in a Cell Type-Dependent and MCK-2-Independent Manner

Many viruses initiate interaction with target cells by binding to cell surface glycosaminoglycans (GAGs). Heparan sulfate (HS) appears to be particularly important in fibroblasts, epithelial cells and endothelial cells, where it represents the dominant GAG. How GAGs influence viral infectivity in HS...

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Bibliographic Details
Main Authors: Sergio M Pontejo, Philip M Murphy
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Viruses
Subjects:
cytomegalovirus
hcmv
mcmv
viral cell entry
glycosaminoglycans
heparan sulfate
chondroitin sulfate
viral chemokines
mck-2
Online Access:https://www.mdpi.com/1999-4915/12/1/31

Internet

https://www.mdpi.com/1999-4915/12/1/31

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