Hippocampal synthesis of sex steroids and corticosteroids: essential for modulation of synaptic plasticity

Hippocampal synthesis of sex steroids and corticosteroids: essential for modulation of synaptic plasticity

Sex steroids play essential roles in the modulation of synaptic plasticity and neuroprotection in the hippocampus. Accumulating evidence shows that hippocampal neurons synthesize both estrogen and androgen. Recently, we also revealed the hippocampal synthesis of corticosteroids. The accurate concent...

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Bibliographic Details
Main Authors: Yasushi eHojo, Shimpei eHigo, Suguru eKawato, Yusuke eHatanaka, Yuuki eOoishi, Gen eMurakami, Hirotaka eIshii, Yoshimasa eKomatsuzaki, Mari eOgiue-Ikeda, Hideo eMukai, Tetsuya eKimoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-10-01
Series:Frontiers in Endocrinology
Subjects:
Hippocampus
synaptic plasticity
corticosteroid
estrogen
sex steroid
androgen
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2011.00043/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2011.00043/full

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