Treatment of Parkinson’s disease using focused ultrasound with GDNF retrovirus-loaded microbubbles to open the blood–brain barrier

Treatment of Parkinson’s disease using focused ultrasound with GDNF retrovirus-loaded microbubbles to open the blood–brain barrier

This study aims to prepare ultrasound-targeted glial cell-derived neurotrophic factor (GDNF) retrovirus-loaded microbubbles (M pLXSN-GDNF) to verify the properties of the microbubbles and to study the therapeutic effect of the GDNF retrovirus-loaded microbubbles combined with ultrasound (U) to open...

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Bibliographic Details
Main Authors: Wang Feng, Li Nana, Hou Ruanling, Wang Lu, Zhang Libin, Li Chenzhang, Zhang Yu, Yin Yaling, Chang Liansheng, Cheng Yuan, Wang Yongling, Lu Jianping
Format: Article
Language:English
Published: De Gruyter 2020-08-01
Series:Open Chemistry
Subjects:
cationic microbubble
parkinson’s disease
retrovirus
gdnf
Online Access:https://doi.org/10.1515/chem-2020-0142

Internet

https://doi.org/10.1515/chem-2020-0142

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