Folic Acid Alleviates High Glucose and Fat-Induced Pyroptosis via Inhibition of the Hippo Signal Pathway on H9C2 Cells

Folic Acid Alleviates High Glucose and Fat-Induced Pyroptosis via Inhibition of the Hippo Signal Pathway on H9C2 Cells

Diabetic cardiomyopathy (DCM) is the leading cause of death in diabetic patients. Folic acid has a protective effect on diabetes-induced cardiomyocyte damage. The aim of this study was to explore the effects of folic acid on cardiomyocytes cultured under high glucose and fat (HGF) conditions and typ...

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Bibliographic Details
Main Authors: Lei Hong, Yingjie Zha, Chen Wang, Shigang Qiao, Jianzhong An
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
type 2 diabetes
diabetic cardiomyopathy
folic acid
pyroptosis
hippo signal pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.698698/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2021.698698/full

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