Bone marrow niche-mediated survival of leukemia stem cells in acute myeloid leukemia: Yin and Yang
Acute myeloid leukemia (AML) is characterized by the accumulation of circulating immature blasts that exhibit uncontrolled growth, lack the ability to undergo normal differentiation, and have decreased sensitivity to apoptosis. Accumulating evidence shows the bone marrow (BM) niche is critical to th...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
China Anti-Cancer Association
2016-06-01
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| Series: | Cancer Biology & Medicine |
| Subjects: | |
| Online Access: | http://www.cancerbiomed.org/index.php/cocr/article/view/930 |