A Human DPP4-Knockin Mouse’s Susceptibility to Infection by Authentic and Pseudotyped MERS-CoV

A Human DPP4-Knockin Mouse’s Susceptibility to Infection by Authentic and Pseudotyped MERS-CoV

Infection by the Middle East respiratory syndrome coronavirus (MERS-CoV) causes respiratory illness and has a high mortality rate (~35%). The requirement for the virus to be manipulated in a biosafety level three (BSL-3) facility has impeded development of urgently-needed antiviral agents. Here, we...

Full description

Bibliographic Details
Main Authors: Changfa Fan, Xi Wu, Qiang Liu, Qianqian Li, Susu Liu, Jianjun Lu, Yanwei Yang, Yuan Cao, Weijin Huang, Chunnan Liang, Tianlei Ying, Shibo Jiang, Youchun Wang
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Viruses
Subjects:
mouse model
hDPP4
MERS-CoV
pseudotyped virus
authentic virus
Online Access:http://www.mdpi.com/1999-4915/10/9/448

Internet

http://www.mdpi.com/1999-4915/10/9/448

Similar Items