IDH Signalling Pathway in Cholangiocarcinoma: from Biological Rationale to Therapeutic Targeting

IDH Signalling Pathway in Cholangiocarcinoma: from Biological Rationale to Therapeutic Targeting

Biliary tract cancers are anatomically distinct and genetically diverse tumors, evenly characterized by poor response to standard treatments and a bleak outlook. The advent of comprehensive genomic profiling using next-generation sequencing has unveiled a plethora of potentially actionable aberratio...

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Bibliographic Details
Main Authors: Massimiliano Salati, Francesco Caputo, Cinzia Baldessari, Barbara Galassi, Francesco Grossi, Massimo Dominici, Michele Ghidini
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
biliary cancer
cholangiocarcinoma
gallbladder cancer
IDH
targeted therapy
precision medicine
Online Access:https://www.mdpi.com/2072-6694/12/11/3310

Internet

https://www.mdpi.com/2072-6694/12/11/3310

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