Thrombolytic Therapy During ex-vivo Normothermic Machine Perfusion of Human Livers Reduces Peribiliary Vascular Plexus Injury
Background: A major limitation in expanding the use of donation after circulatory death (DCD) livers in transplantation is the increased risk of graft failure secondary to ischemic cholangiopathy. Warm ischemia causes thrombosis and injury to the peribiliary vascular plexus (PVP), which is supplied...
Main Authors: | Omar Haque, Siavash Raigani, Ivy Rosales, Cailah Carroll, Taylor M. Coe, Sofia Baptista, Heidi Yeh, Korkut Uygun, Francis L. Delmonico, James F. Markmann |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-06-01
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Series: | Frontiers in Surgery |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2021.644859/full |
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