Epitope Classification and RBD Binding Properties of Neutralizing Antibodies Against SARS-CoV-2 Variants of Concern

Epitope Classification and RBD Binding Properties of Neutralizing Antibodies Against SARS-CoV-2 Variants of Concern

Severe acute respiratory syndrome coronavirus-2 (SAR-CoV-2) causes coronavirus disease 2019 (COVID19) that is responsible for short and long-term disease, as well as death, in susceptible hosts. The receptor binding domain (RBD) of the SARS-CoV-2 Spike (S) protein binds to cell surface angiotensin c...

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Bibliographic Details
Main Authors: Ashlesha Deshpande, Bethany D. Harris, Luis Martinez-Sobrido, James J. Kobie, Mark R. Walter
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
variant of concern
neutralizing antibodies
RBD
ACE2 binding affinity
epitope mapping
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.691715/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.691715/full

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