A multi-antigen vaccine in combination with an immunotoxin targeting tumor-associated fibroblast for treating murine melanoma

A therapeutically effective cancer vaccine must generate potent antitumor immune responses and be able to overcome tolerance mechanisms mediated by the progressing tumor itself. Previous studies showed that glycoprotein 100 (gp100), tyrosinase-related protein 1 (TRP1), and tyrosinase-related protein...

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Bibliographic Details
Main Authors: Jinxu Fang, Biliang Hu, Si Li, Chupei Zhang, Yarong Liu, Pin Wang
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770516300468