DLA class II alleles and haplotypes are associated with risk for and protection from chronic hepatitis in the English Springer spaniel.

Chronic hepatitis (CH) is common in dogs in the United Kingdom. An increased prevalence of the disease is seen in the English Springer spaniel (ESS), and this breed suffer from a severe form with young to middle aged female dogs being predisposed. The disease shares histological features with those...

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Bibliographic Details
Main Authors: Nicholas H Bexfield, Penny J Watson, Jesús Aguirre-Hernandez, David R Sargan, Laurence Tiley, Jonathan L Heeney, Lorna J Kennedy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3411618?pdf=render