Comparison of the central human and mouse platelet signaling cascade by systems biological analysis

Abstract Background Understanding the molecular mechanisms of platelet activation and aggregation is of high interest for basic and clinical hemostasis and thrombosis research. The central platelet protein interaction network is involved in major responses to exogenous factors. This is defined by sy...

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Bibliographic Details
Main Authors: Johannes Balkenhol, Kristin V. Kaltdorf, Elmina Mammadova-Bach, Attila Braun, Bernhard Nieswandt, Marcus Dittrich, Thomas Dandekar
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-020-07215-4