Synthesis of diverse indole libraries on polystyrene resin – Scope and limitations of an organometallic reaction on solid supports
The synthesis of diverse substituted indole structures on solid supports is described. The immobilization of nitrobenzoic acid onto Merrifield resin and the subsequent treatment with alkenyl Grignard reagents delivered indole carboxylates bound to solid supports. In contrast to results in the liquid...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2012-07-01
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Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.8.132 |