Airway basal stem cells generate distinct subpopulations of PNECs

Summary: Pulmonary neuroendocrine cells (PNECs) have crucial roles in airway physiology and immunity by producing bioactive amines and neuropeptides (NPs). A variety of human diseases exhibit PNEC hyperplasia. Given accumulated evidence that PNECs represent a heterogenous population of cells, we inv...

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Bibliographic Details
Main Authors: Hongmei Mou, Ying Yang, Molly A. Riehs, Juliana Barrios, Manjunatha Shivaraju, Adam L. Haber, Daniel T. Montoro, Kimberly Gilmore, Elisabeth A. Haas, Brankica Paunovic, Jayaraj Rajagopal, Sara O. Vargas, Robin L. Haynes, Alan Fine, Wellington V. Cardoso, Xingbin Ai
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Cell Reports
Subjects:
NEB
BSC
NP
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721003259