Cell models of arrhythmogenic cardiomyopathy: advances and opportunities

Arrhythmogenic cardiomyopathy is a rare genetic disease that is mostly inherited as an autosomal dominant trait. It is associated predominantly with mutations in desmosomal genes and is characterized by the replacement of the ventricular myocardium with fibrous fatty deposits, arrhythmias and a high...

Full description

Bibliographic Details
Main Authors: Elena Sommariva, Ilaria Stadiotti, Gianluca L. Perrucci, Claudio Tondo, Giulio Pompilio
Format: Article
Language:English
Published: The Company of Biologists 2017-07-01
Series:Disease Models & Mechanisms
Subjects:
ACM
Online Access:http://dmm.biologists.org/content/10/7/823