Comparing the efficacy of γ- and electron-irradiation of PBMCs to promote secretion of paracrine, regenerative factors

Comparing the efficacy of γ- and electron-irradiation of PBMCs to promote secretion of paracrine, regenerative factors

Cell-free secretomes represent a promising new therapeutic avenue in regenerative medicine, and γ-irradiation of human peripheral blood mononuclear cells (PBMCs) has been shown to promote the release of paracrine factors with high regenerative potential. Recently, the use of alternative irradiation...

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Bibliographic Details
Main Authors: Maria Laggner, Alfred Gugerell, Dragan Copic, Markus Jeitler, Michael Springer, Anja Peterbauer, Christopher Kremslehner, Manuel Filzwieser-Narzt, Florian Gruber, Sibylle Madlener, Michael Erb, Joachim Widder, Wolfgang Lechner, Dietmar Georg, Michael Mildner, Hendrik Jan Ankersmit
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
regenerative medicine
cell-free secretomes
paracrine factors
biological medicinal products
γ-irradiation
electron-irradiation
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050121000310

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http://www.sciencedirect.com/science/article/pii/S2329050121000310

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