Host HLA B*allele-associated multi-clade Gag T-cell recognition correlates with slow HIV-1 disease progression in antiretroviral therapy-naïve Ugandans.

Host HLA B*allele-associated multi-clade Gag T-cell recognition correlates with slow HIV-1 disease progression in antiretroviral therapy-naïve Ugandans.

Some HIV infected individuals remain asymptomatic for protracted periods of time in the absence of antiretroviral therapy (ART). Virological control, CD4 T cell loss and HIV-specific responses are some of the key interrelated determinants of HIV-1 disease progression. In this study, possible interac...

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Bibliographic Details
Main Authors: Jennifer Serwanga, Leigh Anne Shafer, Edward Pimego, Betty Auma, Christine Watera, Samantha Rowland, David Yirrell, Pietro Pala, Heiner Grosskurth, Jimmy Whitworth, Frances Gotch, Pontiano Kaleebu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2617765?pdf=render

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http://europepmc.org/articles/PMC2617765?pdf=render

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