TnseqDiff: identification of conditionally essential genes in transposon sequencing studies

TnseqDiff: identification of conditionally essential genes in transposon sequencing studies

Abstract Background Tn-Seq is a high throughput technique for analysis of transposon mutant libraries to determine conditional essentiality of a gene under an experimental condition. A special feature of the Tn-seq data is that multiple mutants in a gene provides independent evidence to prioritize t...

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Bibliographic Details
Main Authors: Lili Zhao, Mark T. Anderson, Weisheng Wu, Harry L. T. Mobley, Michael A. Bachman
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Bioinformatics
Subjects:
Transposon sequencing
Essential gene
Differential test
Tn-Seq
InSeq
CD function
Online Access:http://link.springer.com/article/10.1186/s12859-017-1745-2

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http://link.springer.com/article/10.1186/s12859-017-1745-2

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