Regulated expression of miR-155 is required for iNKT cell development

Regulated expression of miR-155 is required for iNKT cell development

Invariant Natural Killer T cells (iNKT cells) are CD1d-restricted, lipid antigen–reactive T lymphocytes with immunoregulatory functions. iNKT cell development in the thymus proceeds through subsequent stages, defined by the expression of CD44 and NK1.1, and is dictated by a unique gene expression pr...

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Bibliographic Details
Main Authors: Alessia eBurocchi, Paola ePittoni, Esmerina eTili, Alice eRigoni, Stefan eCostinean, Carlo Maria Croce, MARIO Paolo COLOMBO
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Immunology
Subjects:
Gene Expression Regulation
microRNA
transgenic
thymic development
iNKT cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00140/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00140/full

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