Engineering processive DNA polymerases with maximum benefit and minimum cost
DNA polymerases need to be engineered to achieve optimal performance for biotechnological applications, which often require high fidelity replication when using modified nucleotides and when replicating difficult DNA sequences. These tasks are achieved for the bacteriophage T4 DNA polymerase by rep...
Main Authors: | Linda J. Reha-Krantz, Sandra eWoodgate, Myron F. Goodman |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-08-01
|
Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00380/full |
Similar Items
-
Accuracy of replication in the polymerase chain reaction. Comparison between Thermotoga maritima DNA polymerase and Thermus aquaticus DNA polymerase
by: R.S. Diaz, et al.
Published: (1998-10-01) -
Fidelity of nucleotide incorporation by the human mitochondrial DNA polymerase
by: Lee, Harold Ray
Published: (2008) -
DNA Polymerases in Biotechnology
Published: (2015) -
PHOSPHORYLATION OF DNA POLYMERASE ALPHA IN NORMAL AND ROUS SARCOMA VIRUS TRANSFORMED RAT FIBROBLASTS.
by: DONALDSON, ROBERT WILLIAM.
Published: (1987) -
Kinetics of DNA polymerase conformational changes during nucleotide binding and incorporation
by: Tsai, Yu-chih
Published: (2008)