In vivo and in vitro evidence for placental DNA damage in preeclampsia.

Preeclampsia (PE) is an idiopathic multisystem disease affecting 5-7% of pregnant women. Placental oxidative stress is a characteristic feature of PE and occurs when the production of reactive oxygen species (ROS) within the placenta overwhelms the intrinsic anti-oxidant defenses. We hypothesize tha...

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Bibliographic Details
Main Authors: Serkalem Tadesse, Dawit Kidane, Seth Guller, Tianmeng Luo, Nicholas G Norwitz, Felice Arcuri, Paolo Toti, Errol R Norwitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3899334?pdf=render