Elucidation of signaling and functional activities of an orphan GPCR, GPR81

Elucidation of signaling and functional activities of an orphan GPCR, GPR81

GPR81 is an orphan G protein-coupled receptor (GPCR) that has a high degree of homology to the nicotinic acid receptor GPR109A. GPR81 expression is highly enriched and specific in adipocytes. However, the function and signaling properties of GPR81 are unknown because of the lack of natural or synthe...

Full description

Bibliographic Details
Main Authors: Hongfei Ge, Jennifer Weiszmann, Jeff D. Reagan, Jamila Gupte, Helene Baribault, Tibor Gyuris, Jin-Long Chen, Hui Tian, Yang Li
Format: Article
Language:English
Published: Elsevier 2008-04-01
Series:Journal of Lipid Research
Subjects:
G protein-coupled receptor
dyslipidemia
niacin
GPR109A
free fatty acid
HDL
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520423934

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520423934

Similar Items