West Nile Virus Temperature Sensitivity and Avian Virulence Are Modulated by NS1-2B Polymorphisms.

West Nile virus (WNV) replicates in a wide variety of avian species, which serve as reservoir and amplification hosts. WNV strains isolated in North America, such as the prototype strain NY99, elicit a highly pathogenic response in certain avian species, notably American crows (AMCRs; Corvus brachyr...

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Bibliographic Details
Main Authors: Elizabeth A Dietrich, Stanley A Langevin, Claire Y-H Huang, Payal D Maharaj, Mark J Delorey, Richard A Bowen, Richard M Kinney, Aaron C Brault
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4993437?pdf=render