A beneficiary role for neuraminidase in influenza virus penetration through the respiratory mucus.

Swine influenza virus (SIV) has a strong tropism for pig respiratory mucosa, which consists of a mucus layer, epithelium, basement membrane and lamina propria. Sialic acids present on the epithelial surface have long been considered to be determinants of influenza virus tropism. However, mucus which...

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Bibliographic Details
Main Authors: Xiaoyun Yang, Lennert Steukers, Katrien Forier, Ranhua Xiong, Kevin Braeckmans, Kristien Van Reeth, Hans Nauwynck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4198190?pdf=render