Oncolytic peptide LTX-315 induces an immune-mediated abscopal effect in a rat sarcoma model

Oncolytic peptide LTX-315 induces an immune-mediated abscopal effect in a rat sarcoma model

LTX 315 is an oncolytic peptide with potent immunological properties. In the present study, we demonstrate that intratumoral treatment with LTX-315 resulted in a complete regression and systemic immune response in a rat fibrosarcoma model. The treatment was T-cell dependent, and also resulted in an...

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Bibliographic Details
Main Authors: Janne Nestvold, Meng-Yu Wang, Ketil A. Camilio, Severin Zinöcker, Torunn Elisabeth Tjelle, Alf Lindberg, Bengt Erik Haug, Gunnar Kvalheim, Baldur Sveinbjørnsson, Øystein Rekdal
Format: Article
Language:English
Published: Taylor & Francis Group 2017-08-01
Series:OncoImmunology
Subjects:
sarcoma
damp
immunotherapy
oncolytic peptide
ltx-315
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1338236

Internet

http://dx.doi.org/10.1080/2162402X.2017.1338236

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