Association Between Glucocerebrosidase Mutations and Parkinson's Disease in Ireland

Association Between Glucocerebrosidase Mutations and Parkinson's Disease in Ireland

Multiple studies implicate heterozygous GBA mutations as a major genetic risk factor for Parkinson's disease (PD); however, the frequency of mutations has never been examined in PD patients from the Irish population. We prospectively recruited 314 unrelated Irish PD patients (UK Brain Bank Crit...

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Bibliographic Details
Main Authors: Diana A. Olszewska, Allan McCarthy, Alexandra I. Soto-Beasley, Ronald L. Walton, Brian Magennis, Russell L. McLaughlin, Orla Hardiman, Owen A. Ross, Tim Lynch
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neurology
Subjects:
GBA
glucocerebrosidase
Ireland
sequencing
Parkinson's disease
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00527/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00527/full

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