The use of ultrasensitive quantitative-PCR to assess the impact of primaquine on asymptomatic relapse of Plasmodium vivax infections: a randomized, controlled trial in Lao PDR

The use of ultrasensitive quantitative-PCR to assess the impact of primaquine on asymptomatic relapse of Plasmodium vivax infections: a randomized, controlled trial in Lao PDR

Abstract Background Trials to assess the efficacy of the radical cure of Plasmodium vivax malaria with 8-aminoquinolines require that most post-treatment relapses are identified, but there is no consensus on the optimal duration of follow-up in either symptomatic or asymptomatic vivax malaria. The e...

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Bibliographic Details
Main Authors: Koukeo Phommasone, Frank van Leth, Mallika Imwong, Gisela Henriques, Tiengkham Pongvongsa, Bipin Adhikari, Thomas J. Peto, Cholrawee Promnarate, Mehul Dhorda, Pasathorn Sirithiranont, Mavuto Mukaka, Pimnara Peerawaranun, Nicholas P. J. Day, Frank Cobelens, Arjen M. Dondorp, Paul N. Newton, Nicholas J. White, Lorenz von Seidlein, Mayfong Mayxay
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Malaria Journal
Subjects:
Malaria
P. vivax
PCR
Primaquine
Relapse
Online Access:https://doi.org/10.1186/s12936-019-3091-5

Internet

https://doi.org/10.1186/s12936-019-3091-5

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