Hepatitis C virus genotypes 1–3 infections regulate lipogenic signaling and suppress cholesterol biosynthesis in hepatocytes

Hepatitis C virus genotypes 1–3 infections regulate lipogenic signaling and suppress cholesterol biosynthesis in hepatocytes

Background: Patients with different hepatitis C virus (HCV) genotype infections are associated with varying metabolic disorders. Although alteration of lipid metabolism has been confirmed as a virus-induced metabolic derangement in chronic hepatitis C patients, the impact of various HCV genotypes on...

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Bibliographic Details
Main Authors: Ching-Sheng Hsu, Wei-Liang Liu, Qisheng Li, Brianna Lowey, Laura Hertz, You-Chen Chao, T. Jake Liang, Ding-Shinn Chen, Jia-Horng Kao
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Journal of the Formosan Medical Association
Subjects:
Genotype
Human
Lipid metabolism
Metabolic diseases
Sofosbuvir
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664620301108

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http://www.sciencedirect.com/science/article/pii/S0929664620301108

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