Design, Synthesis and Biological Evaluation of Novel Triazole <em>N</em>-acylhydrazone Hybrids for Alzheimer’s Disease

Design, Synthesis and Biological Evaluation of Novel Triazole <em>N</em>-acylhydrazone Hybrids for Alzheimer’s Disease

<i>Alzheimer’s disease</i> (AD) is a <i>multifactorial</i> neurodegenerative disorder that involves different pathogenic mechanisms. In this regard, the goal of this study was the design and synthesis of new compounds with multifunctional pharmacological activity by molecular...

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Bibliographic Details
Main Authors: Matheus de Freitas Silva, Ellen Tardelli Lima, Letizia Pruccoli, Newton G. Castro, Marcos Jorge R. Guimarães, Fernanda M. R. da Silva, Nathalia Fonseca Nadur, Luciana Luiz de Azevedo, Arthur Eugen Kümmerle, Isabella Alvim Guedes, Laurent Emmanuel Dardenne, Vanessa Silva Gontijo, Andrea Tarozzi, Claudio Viegas
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
molecular hybridization
Alzheimer’s disease
curcumin
resveratrol
Online Access:https://www.mdpi.com/1420-3049/25/14/3165

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https://www.mdpi.com/1420-3049/25/14/3165

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