Complement Factor H-Related Protein 4A Is the Dominant Circulating Splice Variant of CFHR4

Recent research has elucidated circulating levels of almost all factor H-related (FHR) proteins. Some of these proteins are hypothesized to act as antagonists of the important complement regulator factor H (FH), fine-tuning complement regulation on human surfaces. For the CFHR4 splice variants FHR-4...

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Bibliographic Details
Main Authors: Richard B. Pouw, Mieke C. Brouwer, Anna E. van Beek, Mihály Józsi, Diana Wouters, Taco W. Kuijpers
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00729/full