Synthesis of novel amodiaquine analogs and evaluation of their in vitro and in vivo antimalarial activities

Background & objectives: Due to the rapid increase of drug resistance in Plasmodium parasites, there is a pressing need of developing new antiplasmodial drugs. In this study, new amodiaquine (AQ) analogs were synthesized, followed by an evaluation of their antiplasmodial activity. Methods: A new...

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Bibliographic Details
Main Authors: Azar Tahghighi, Arezoo Rafie Parhizgar, Safoura Karimi, Mahboubeh Irani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Journal of Vector Borne Diseases
Subjects:
Online Access:http://www.jvbd.org/article.asp?issn=0972-9062;year=2019;volume=56;issue=3;spage=221;epage=230;aulast=Tahghighi