Proteomic analysis of aged microglia: shifts in transcription, bioenergetics, and nutrient response

Proteomic analysis of aged microglia: shifts in transcription, bioenergetics, and nutrient response

Abstract Background Age is the primary risk factor for many diseases. As such, age is a critical co-factor for examination in order to understand the progression and potential intervention in disease progression. Studies examining both the phenotype and transcriptome of aged microglia demonstrated a...

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Bibliographic Details
Main Authors: Antwoine Flowers, Harris Bell-Temin, Ahmad Jalloh, Stanley M. Stevens, Paula C. Bickford
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Journal of Neuroinflammation
Subjects:
Insulin Growth Factor
Microglial Phenotype
Microglial Function
Upstream Regulator Analysis
Aged Microglia
Online Access:http://link.springer.com/article/10.1186/s12974-017-0840-7

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http://link.springer.com/article/10.1186/s12974-017-0840-7

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