Experimental and modeling study of the formation of cell aggregates with differential substrate adhesion.

The study of cell aggregation in vitro has a tremendous importance these days. In cancer biology, aggregates and spheroids serve as model systems and are considered as pseudo-tumors that are more realistic than 2D cell cultures. Recently, in the context of brain tumors (gliomas), we developed a new...

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Bibliographic Details
Main Authors: Léo Adenis, Emilie Gontran, Christophe Deroulers, Basile Grammaticos, Marjorie Juchaux, Olivier Seksek, Mathilde Badoual
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0222371