Engraftment of Bacteria after Fecal Microbiota Transplantation Is Dependent on Both Frequency of Dosing and Duration of Preparative Antibiotic Regimen

Engraftment of Bacteria after Fecal Microbiota Transplantation Is Dependent on Both Frequency of Dosing and Duration of Preparative Antibiotic Regimen

The gut microbiota has emerged as a key mediator of human physiology, and germ-free mice have been essential in demonstrating a role for the microbiome in disease. Preclinical models using conventional mice offer the advantage of working with a mature immune system. However, optimal protocols for fe...

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Bibliographic Details
Main Authors: Vancheswaran Gopalakrishnan, Elizabeth Ashley Dozier, Matthew S. Glover, Steven Novick, Michael Ford, Christopher Morehouse, Paul Warrener, Carolina Caceres, Sonja Hess, Bret R. Sellman, Taylor S. Cohen
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Microorganisms
Subjects:
microbiome
conventional mice
antibiotics
engraftment
Online Access:https://www.mdpi.com/2076-2607/9/7/1399

Internet

https://www.mdpi.com/2076-2607/9/7/1399

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