TNF-α induces acyl-CoA synthetase 3 to promote lipid droplet formation in human endothelial cells

Chronic inflammation contributes to cardiovascular disease. Increased levels of the inflammatory cytokine, TNF-α, are often present in conditions associated with cardiovascular disease risk, and TNF-α induces a number of pro-atherogenic effects in macrovascular endothelial cells, including expressio...

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Bibliographic Details
Main Authors: Hye Seung Jung, Masami Shimizu-Albergine, Xia Shen, Farah Kramer, Dan Shao, Anuradha Vivekanandan-Giri, Subramaniam Pennathur, Rong Tian, Jenny E. Kanter, Karin E. Bornfeldt
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520300146