Comparative proteomic analysis reveals characteristic molecular changes accompanying the transformation of nonmalignant to cancer lung cells

Comparative proteomic analysis reveals characteristic molecular changes accompanying the transformation of nonmalignant to cancer lung cells

To identify changes in proteins accompanying transformation of normal lung epithelial cells to cancer cells, we performed a comparative proteomic study using two cell lines representing matching normal and cancer cells. Strikingly, a good number of detected actin cytoskeletal proteins were preferent...

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Bibliographic Details
Main Authors: Daniela Cadinu, Jagmohan Hooda, Md Maksudul Alam, Parimaladevi Balamurugan, Robert M. Henke, Li Zhang
Format: Article
Language:English
Published: Elsevier 2014-06-01
Series:EuPA Open Proteomics
Subjects:
iTRAQ
Proteomic
Lung cancer
Actin cytoskeleton
Protein network
Online Access:http://www.sciencedirect.com/science/article/pii/S2212968514000026

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http://www.sciencedirect.com/science/article/pii/S2212968514000026

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