Prospective detection of mutations in cerebrospinal fluid, pleural effusion, and ascites of advanced cancer patients to guide treatment decisions

Prospective detection of mutations in cerebrospinal fluid, pleural effusion, and ascites of advanced cancer patients to guide treatment decisions

Many advanced cases of cancer show central nervous system, pleural, or peritoneal involvement. In this study, we prospectively analyzed if cerebrospinal fluid (CSF), pleural effusion (PE), and/or ascites (ASC) can be used to detect driver mutations and guide treatment decisions. We collected 42 CSF,...

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Bibliographic Details
Main Authors: Sergio Villatoro, Clara Mayo‐de‐las‐Casas, Núria Jordana‐Ariza, Santiago Viteri‐Ramírez, Mónica Garzón‐Ibañez, Irene Moya‐Horno, Beatriz García‐Peláez, María González‐Cao, Umberto Malapelle, Ariadna Balada‐Bel, Alejandro Martínez‐Bueno, Raquel Campos, Noemí Reguart, Margarita Majem, Remei Blanco, Ana Blasco, María J. Catalán, Xavier González, Giancarlo Troncone, Niki Karachaliou, Rafael Rosell, Miguel A. Molina‐Vila
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Molecular Oncology
Subjects:
ascites
cell‐free DNA
cerebrospinal fluid
liquid biopsy
pleural effusion
solid tumors
Online Access:https://doi.org/10.1002/1878-0261.12574

Internet

https://doi.org/10.1002/1878-0261.12574

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