The IL-12 Cytokine and Receptor Family in Graft-vs.-Host Disease

Allogeneic hematopoietic cell transplantation (allo-HCT) is performed with curative intent for high- risk blood cancers and bone marrow failure syndromes; yet the development of acute and chronic graft-vs.-host disease (GVHD) remain preeminent causes of death and morbidity. The IL-12 family of cytok...

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Bibliographic Details
Main Authors: David Bastian, Yongxia Wu, Brian C. Betts, Xue-Zhong Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
GVT
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00988/full