Granulocyte colony-stimulating factor reduces fibrosis in a mouse model of chronic pancreatitis.

Chronic pancreatitis (CP) is a necroinflammatory process resulting in extensive pancreatic fibrosis. Granulocyte colony-stimulating factor (G-CSF), a hematopoietic stem cell mobilizer, has been shown to exert an anti-fibrotic effect partly through the enrichment of bone marrow (BM) cells in fibrotic...

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Bibliographic Details
Main Authors: Wey-Ran Lin, Tzung-Hai Yen, Siew-Na Lim, Ming-Der Perng, Chun-Yen Lin, Ming-Yo Su, Chau-Ting Yeh, Cheng-Tang Chiu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4281240?pdf=render