Roles of pRB in the Regulation of Nucleosome and Chromatin Structures
Retinoblastoma protein (pRB) interacts with E2F and other protein factors to play a pivotal role in regulating the expression of target genes that induce cell cycle arrest, apoptosis, and differentiation. pRB controls the local promoter activity and has the ability to change the structure of nucleos...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2016-01-01
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| Series: | BioMed Research International |
| Online Access: | http://dx.doi.org/10.1155/2016/5959721 |