Daily rhythms of plasma melatonin, but not plasma leptin or leptin mRNA, vary between lean, obese and type 2 diabetic men.

Daily rhythms of plasma melatonin, but not plasma leptin or leptin mRNA, vary between lean, obese and type 2 diabetic men.

Melatonin and leptin exhibit daily rhythms that may contribute towards changes in metabolic physiology. It remains unclear, however, whether this rhythmicity is altered in obesity or type 2 diabetes (T2DM). We tested the hypothesis that 24-hour profiles of melatonin, leptin and leptin mRNA are alter...

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Bibliographic Details
Main Authors: Simone Mäntele, Daniella T Otway, Benita Middleton, Silvia Bretschneider, John Wright, M Denise Robertson, Debra J Skene, Jonathan D Johnston
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3356389?pdf=render

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http://europepmc.org/articles/PMC3356389?pdf=render

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