Investigation of multi-trait associations using pathway-based analysis of GWAS summary statistics

Investigation of multi-trait associations using pathway-based analysis of GWAS summary statistics

Abstract Background Genome-wide association studies (GWAS) have been successful in identifying disease-associated genetic variants. Recently, an increasing number of GWAS summary statistics have been made available to the research community, providing extensive repositories for studies of human comp...

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Bibliographic Details
Main Authors: Guangsheng Pei, Hua Sun, Yulin Dai, Xiaoming Liu, Zhongming Zhao, Peilin Jia
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Genomics
Subjects:
GWAS
Pathway enrichment analysis
Multi-dimensional scaling
Cross-trait association
Summary statistics
Pleiotropy abbreviations
Online Access:http://link.springer.com/article/10.1186/s12864-018-5373-7

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http://link.springer.com/article/10.1186/s12864-018-5373-7

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