Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells

Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells

Abstract Background Peptide-drug-conjugates (PDCs) are being developed as an effective strategy to specifically deliver cytotoxic drugs to cancer cells. However one of the challenges to their successful application is the relatively low stability of peptides in the blood, liver and kidneys. Since Au...

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Bibliographic Details
Main Authors: Kalishwaralal Kalimuthu, Bat-Chen Lubin, Andrii Bazylevich, Gary Gellerman, Ofer Shpilberg, Galia Luboshits, Michael A. Firer
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Nanobiotechnology
Subjects:
Targeted drug delivery
Peptide drug conjugates
Phage display
Gold nanoparticles
Online Access:http://link.springer.com/article/10.1186/s12951-018-0362-1

Internet

http://link.springer.com/article/10.1186/s12951-018-0362-1

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