Aryl Hydrocarbon Receptor Antagonists Mitigate the Effects of Dioxin on Critical Cellular Functions in Differentiating Human Osteoblast-Like Cells

Aryl Hydrocarbon Receptor Antagonists Mitigate the Effects of Dioxin on Critical Cellular Functions in Differentiating Human Osteoblast-Like Cells

The inhibition of bone healing in humans is a well-established effect associated with cigarette smoking, but the underlying mechanisms are still unclear. Recent work using animal cell lines have implicated the aryl hydrocarbon receptor (AhR) as a mediator of the anti-osteogenic effects of cigarette...

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Bibliographic Details
Main Authors: Chawon Yun, Karina M. Katchko, Michael S. Schallmo, Soyeon Jeong, Jonghwa Yun, Charlotte H. Chen, Joseph A. Weiner, Christian Park, Andrew George, Samuel I. Stupp, Wellington K. Hsu, Erin L. Hsu
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
TCDD
dioxin
bone healing
smoking
aryl hydrocarbon receptor
Online Access:http://www.mdpi.com/1422-0067/19/1/225

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http://www.mdpi.com/1422-0067/19/1/225

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